Relafen and diabetes

Relafen		$31.50
	Relafen is used for treatment of rheumatoid arthritis or osteoarthritis. It may also be used for other conditions as determined by your doctor.	More Info Order Now

Latin name
Relafen
The composition and the form
1 tablet, coated nabumetona contains 500 or 750 mg in bottles of 100 pcs., 1 bottle per box.
Pharmacological action
Anti-inflammatory, antipyretic, analgesic.
Pharmacokinetics
After oral administration, the drug is well absorbed in the gastrointestinal tract. Admission simultaneously with food increases the rate of absorption. Treated rapid biotransformation to the principal active metabolite 6-methoxy-2-naphthylacetic acid (6-MNUK). More than 99% 6-MNUK bound to plasma proteins. After oral nabumetona a dose of 1 or 2 g in the equilibrium phase Cl 6-MNUK is 20-30 ml / min, and half-life – about 24 hours
Indications
Osteoarthritis, rheumatoid arthritis.
Pregnancy and lactation
Not recommended.
Contraindications
Hypersensitivity, children’s age.
Side effects
Sleep disturbance, dizziness, headache, fatigue, nervousness, agitation, depression, tremor, paresthesia, visual disturbances, vasculitis, increased blood pressure, tachycardia, myocardial infarction, angina pectoris, syncope, thrombophlebitis, dyspnea, asthma, eosinophilic pneumonia, abdominal pain, gastritis, diarrhea, constipation, flatulence, nausea, vomiting, dry mouth, gastritis, anorexia, jaundice, gastric and duodenal ulcer, dysphagia, gastroenteritis, increase in liver transaminases, duodenitis, gall bladder stones, pancreatitis, gingivitis, glossitis, bleeding from the rectum, anemia, leukopenia, granulocytopenia, thrombocytopenia, albuminuria, hyperuricemia, nephrotic syndrome, interstitial nephritis, dysuria, hematuria, kidney stones, vaginal bleeding, impotence, hives, angioedema, photosensitivity, toxic epidermal necrolysis, polymorphic erythema, Stevens syndrome – Johnson, chills, fever, sweating, alopecia.
Drug Interactions
Actively bound to plasma proteins.
Overdose
Symptoms: abdominal pain. Treatment: Induce vomiting or lavage. To reduce absorption using activated charcoal (60 g). Requires monitoring of vital body functions in a hospital.
Precautions
Caution must be exercised in the appointment of the drug to patients with digestive tract diseases (even in history), weak and elderly (increased risk of gastric ulcers and duodenal ulcers, bleeding and perforation) in patients with impaired renal function and liver, congestive heart failure, arterial hypertension (possible fluid retention in the body).
Dosing and Administration
Inside, regardless of the meal. At 1-2 g 1-2 times a day.